Creating a perfect cancer vaccine inside the body!
Research on "Cancer Vaccines" has been going on for decades with little to show for it. In recent years the effort has switched to personalized vaccines created for each individual patient by removing part of the tumor and presenting it to antigen presenting cell, usually dendrites. I have seen these vaccines slow down progression, but to date they have not produced a workable vaccine to reliably give complete remission.
When you use PDT properly, it creates an "in situ" vaccination which does stimulate the patients immune system to attack the cancer. This does not happen with all sensitizers. We created our sensitizer to give the maximum immune response.
We believe this is a vital part of fighting cancer, because in theory it can make the patient immune to recurrence once the main cancer is under control. The main body of cancer must be reduced to a minimum size before the immune system can gain control, simply because Cancer has ways of resisting the immune system.
We cannot guarantee that all patients will have an excellent immune response, because individuals may have immune system defects or immune suppression, especially if they have been on chemo.
We do know from several years of treating patients that MOST of our patients have an excellent ongoing immune response which continues to shrink tumors and provide protection against recurrence.
Some of the key points of tumour resistance to the immune system have been identified, and there are antibodies which disable this resistance. We use a specific antibody and most of our cancer patients have continuing shrinkage of remaining tumours for months.
In laboratory tests attempts to cause cancer in the test animals cured by PDT showed 100% protection even six months after treatment. Attempts to start cancer in these tests were done 36 times, and it was not possible to start cancer in the test animals.
|These papers are on the use of PDT to create an enduring immune response to cancer via in-situ vaccination.|
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|We did a test on a patient with a breast tumour to see if we could create an immune response and it was successful, according to the lab report which is included below. This indicates the immune system was attacking the cancer and the cancer cells were not multiplying as fast as they had been.|
Clinical Notes: Photodynamic therapy only.
Sections show a core of breast parenchyma in which there is an infiltrating ductal carcinoma of no special type. There is no attempt at ductal formation. The nuclei are enlarged and pleomorphic. Nucleioli are prominant in some cells.
Mitotic figures are present but are relatively few. The tumour is infiltrate by a lymphoid population. There are luge number of lymphocytes and scatter plasma cells but no macrophages or neutrophils are demonstrated. Apoptosis is minimal.
In this sample no tumour is seen within vascular spaces or in a perinaural distribution.
This is a grade 2 ductal carcinoma because of the paucity of mitotic figures. The heavy immunological response may be a response to therapy but there is little necrosis.
SUMMARY: INFILTRATING DUCTAL CARCINOMA OF NO SPECIAL TYPE WITH HEAVY IMMUNOLOGICAL RESPONSE.
Notes: The protocol which preceded this biopsy was designed specifically to reduce mitotic activity and induce an immunological response.
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